Why Natural Pullulan Capsules® Made From Naturally Fermented Pullulans Will Be The Global Health Preferred Option

Natural Pullulan Capsules® are manufactured from the raw materials of naturally fermented pullulans and a few naturally fermented ingredients. It is sourced from sucrose or starch. It is pure plant origin, no chemical and artificially synthetic substances are added, no risks of animal borne diseases, safe and healthy. The capsule is in compliance with the concept of natural and organic which people pursue. It also meets the demand of EU Clean Label and vegetarians, religious and other special people. Pullulan is inert substance, it does no harm to human being and it is not absorbed by the body. It will not burden the human body with metabolism.

The comparison of Gelatin capsules and Pullulan capsules:

ItemGelatin capsulesPullulan capsules
Raw materialsBovine/porcine bone or skinSucrose or starch
Chemical stabilityEasy to crosslink,leading to delay the disintegrating time,reduce capsule contents dissolution,and influence pharmacological action.Chemical inertas well as with some healthcare function
Moisture content12.5%-17.5%10%-13%
Disintegration timeLess than 10min4-7min, generally,6min
FragilityLess than 5 pcs in 50 pcsNone
Oxygen permeabilityThe oxygen permeability is moderate at 25 and 60%RHThe oxygen permeability is the lowest at 25 and 60%RH
SafetyWith potential risk,especially for the emergency of TSE/BSESafe fermented product

Compared with Gelatin capsules, Pullulan capsules have some advantages as following:

The comparison of HPMC capsules and Pullulan capsules:

ItemHPMC capsulesPullulan capsules
Raw materialsPine fiberSucrose or starch
Chemical stabilityChemical inertdo not be involved in the metabolized in the body.Chemical inertas well as with some healthcare function
Moisture content5%-8%10%-13%
Disintegration time4-7min, generally,6min4-7min, generally,6min
FragilityNoneNone
Oxygen permeabilityThe oxygen permeability is the highest at 25 and 60%RHThe oxygen permeability is the lowest at 25 and 60%RH
SafetySafe  Common used coagulants are in compliance with the pharmacopoeia of many countries.Safe fermented product

Compared with HPMC capsules, Pullulan capsules have some advantages as following:

  • Pure natural fermentation, no chemical substances, no maillard reaction
  • No pesticide residues,non-GMO
  • Low oxygen permeability, to protect the content much better
  • The appearance is much brighter, high transparency

Compared with HPMC capsules, the characters of Pullulan capsules are more like Gelatin capsules. The only defect is that the production of Pullulan capsules is low at present, the cost is high, and the price is on high side. However, as the technology matures, with the increase of quantity, the cost will decrease correspondingly, Pullulan capsules are expected to be cheaper than HPMC capsules in the future.